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At 48 h post-treatment, an EC of 8.1 pM ( 2.3 pM) was calculated (Fig

Melatonin also prevents the opening of the mitochondrial permeability transition pore (mPTP) and activates AMPK, promoting cellular energy balance and mitochondrial biogenesis (Ozkok et al., 2016)

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4a, upper chromatogram), but after 1 h of incubation with glucosidase, the first peak, eluting after 1.7 min and representing the paracetamolglucose, completely disappears as a result of hydrolyzing the ester bond between glucose and acetaminophen (see Fig