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As for the latter, these vaccines can remodel the TME including its immune and stromal components leading to a reduction in pro-inflammatory cytokines such as CXCL10 (refs

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-galactosidase activity was detected using X-Gal staining solution (1 mg ml 1 X-gal, Thermo Scientific, 5 mM K 3 (Fe(CN) 6 ) and 5 mM K 4 (Fe(CN) 6 )) diluted in 1 mM MgCl 2 /PBS (pH 5.56) for 818 h at 37 C

The enzalutamide (ENZ, anticancer drug) and folic acid (FA, targeting agent) were covalently conjugated to SBA-15 and the resulted FA-SBA-15/ENZ was loaded with thiolated nitrogen-doped carbon dots (SNCDs) as a fluorescent label for imaging

10.1371/journal.ppat.1005675 PLoS Pathog