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GLP-1 receptor agonists (GLP-1RAs) are currently used for treating type-2 diabetes and obesity because of their effects on appetite, food intake, and body weight loss

You should use them alongside a nutrition and lifestyle program such as the Mayo Clinic Diet for Weight-Loss Medication program

Most studies and clinical trials suggest that semaglutide does not significantly raise the risk of developing AFib compared to other treatments

doi:10.1002/alz.14313

In trials Motus reported about 10.4 percent average weight loss over six months in human clinical trials, with much of the loss coming from fat rather than lean mass