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Stakeholders and the review panel highlighted several areas for improvement, including two important concerns: lack of an accelerated review option in contrast to other developed NRAs and lack of flexibility in making the assessment commensurate with risk, adequate for the type of product approved or the international approval status

An overlooked subset of cx3cr1(wt/wt) microglia in the cx3cr1(creer-eyfp/wt) mouse has a repopulation advantage over cx3cr1(creer-eyfp/wt) microglia following microglial depletion

In a comprehensive SAXS-based study, Semisotnov et al

Whilst the modeled change following censoring using an MMRM approach could have overestimated the treatment effect, the lack of consistency observed with and without censoring is concerning and supportive of our hypothesis

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