Methotrexatebest response in subacute CLE and discoid CLE Immunosuppressives such as azathioprine, mycophenolate and cyclophosphamide Intravenous immunoglobulin Aspirin is recommended for antiphospholipid syndrome

Key points GLP-1 is a hormone that increases insulin release and prevents the release of too much glucagon, helping manage blood glucose levels in individuals with type 2 diabetes GLP-1 receptor agonists, such as liraglutide and semaglutide, effectively reduce blood glucose levels Semaglutide is more effective than liraglutide at reducing blood sugar levels Tirzepatide is a newer GLP-1 receptor agonist that also mimics the actions of another hormone called GIP, which can also reduce blood sugar levels A randomised controlled trial showed that tirzepatide led to more significant blood sugar reductions than semaglutide across three doses Tirzepatide may be more effective than semaglutide at higher doses, but this needs further investigation Liraglutide and semaglutide are available in the UK and the US, while tirzepatide is only available in the US but is likely to be approved in the UK soon
Omaveloxolone: a groundbreaking milestone as the first FDA-approved drug for Friedreich ataxia
One of the most common causes of this inflammation is an underlying condition that leads to swelling in the wrist and sometimes even an obstructed blood flow
Moreover, since QT prolongation can occur with the administration of this medication, a baseline ECG is recommended